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End of Life Care for GPs: Your Survival Guide
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Updated Guidelines 2026: This page incorporates the latest NICE NG142 (End of life care for adults: service delivery) and NG31 (Care of dying adults in the last days of life) guidance, updated March 2026.
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End of Life Care for GPs: Your Survival Guide

Because dignity in dying starts with confidence in caring

🍵 Tea-Friendly Learning
For GP Trainees Short on Time
🚩 Red Flag Focused

Last Updated: March 2026

Executive Summary: What You'll Master Today

Because you have 47 other things to do before lunch, and that's just the morning list

Clinical Skills You'll Gain

  • Recognition: Identify patients approaching end of life using prognostic indicators
  • Communication: Master SPIKES framework for breaking bad news
  • Assessment: Conduct holistic physical, psychological, social, and spiritual assessments
  • Symptom Control: Evidence-based management of pain, breathlessness, nausea
  • Prescribing: Safe anticipatory prescribing and syringe driver principles
  • Emergencies: Recognize and manage palliative emergencies

Legal & Practical Knowledge

  • Capacity: Mental Capacity Act 2005 assessment framework
  • DNACPR: Legal requirements and conversation skills
  • Advance Planning: ADRT, LPA, and advance statements
  • After Death: Verification, certification, and coroner referrals
  • Family Support: Carer assessment and bereavement care
  • Benefits: DS1500, Carer's Allowance, and financial support

📊 Quick Facts That Matter

1%
of population dies each year
75%
want to die at home
45%
actually do (2026 data)

Downloads

Essential clinical resources and downloadable materials

Downloads

path: PALLIATIVE & END OF LIFE CARE

🧠 Brainy Bites: Essential End of Life Care Wisdom

Memory aids and golden rules for confident end-of-life care

Golden Rules

  • Early recognition allows better planning and patient choice
  • Honest communication builds trust and reduces anxiety
  • Symptom control is achievable in 95% of patients
  • Family support is as important as patient care
  • Anticipatory prescribing prevents crisis situations
  • Dignity and comfort are always possible

Remember: You don't need to be a palliative care specialist to provide excellent end-of-life care. You just need to know when to worry, when to treat, and when to refer.

❤️ Now go reward yourself with that well-deserved coffee

Memory Aids & Mnemonics

SPIKES (Breaking Bad News)

Setting, Perception, Invitation, Knowledge, Emotions, Strategy

PAIN Assessment

Palliates/Provokes, Associated symptoms, Intensity, Nature/timing

Hypercalcemia

Stones, Bones, Groans, Moans
(Kidney stones, bone pain, GI symptoms, psychiatric symptoms)

Capacity Assessment

Can they Understand, Retain, Use/weigh, Communicate?

5 Palliative Care Emergencies

Hypercalcemia, severe Haemorrhage, neutropenic Sepsis, Spinal cord compression, Superior vena cava compression

🎯 Recognition & Identification of End of Life

When to start thinking about palliative care

Key Point:

Early identification allows for better planning, symptom control, and patient choice. The "surprise question" - "Would you be surprised if this patient died in the next 12 months?" - is a useful starting point.

CANCER 🎗️ Trajectory

  • • Metastatic disease
  • • Progressive weight loss >10% in 6 months
  • • Declining performance status (ECOG 3-4)
  • • Recurrent hospital admissions
  • • Patient expressing concerns about prognosis

🫁 ORGAN FAILURE Trajectory

  • • Heart failure NYHA Class III-IV
  • • COPD with recurrent exacerbations
  • • CKD Stage 4-5 declining dialysis
  • • Liver failure with ascites/encephalopathy
  • • Multiple hospital admissions

🧠 DEMENTIA/FRAILTY Trajectory

  • • Unable to walk without assistance
  • • Urinary and fecal incontinence
  • • No meaningful conversation
  • • Unable to dress without assistance
  • • Recurrent infections or eating problems

❓ The Surprise Question

"Would you be surprised if this patient died in the next 12 months?"

If the answer is NO, consider:

  • • Advance care planning discussions
  • • Palliative care referral
  • • DNACPR discussion if appropriate
  • • Preferred place of care conversation
  • • Anticipatory prescribing

🥇 Gold Standards Framework

Three stages of identification:

🟢 GREEN: Stable but advancing disease (years prognosis)
🟡 YELLOW: Unstable, deteriorating (months prognosis)
🔴 RED: Last days/weeks of life

💬 Communication & Breaking Bad News

Having those difficult conversations

🗣️ SPIKES Framework for Breaking Bad News

Step Action Example
Setting Private, comfortable environment. Sit down, maintain eye contact. Allow adequate time. Have tissues available. Consider who else should be present. Private room, tissues, turn off phone
Perception Find out what they already know "What is your understanding of your condition?" "What have the doctors told you so far?" "What are your main concerns?"
Invitation Ask permission to share information "Would you like me to explain what the tests show?" "How much detail would you like me to go into?" "Are you the sort of person who likes to know everything?"
Knowledge Share information sensitively Use simple, clear language. Give information in small chunks. Use warning shots: "I'm afraid I have some difficult news..." Pause frequently to check understanding
Emotions Respond to emotions with empathy "I can see this is very difficult news" "This must be frightening for you" Allow silence and tears. Offer practical support
Strategy Plan next steps together "What questions do you have?" "What are your main concerns now?" "Who can we involve to help you?" Arrange follow-up

💬 Useful Conversation Starters & Phrases

Opening difficult conversations:
  • • "I'd like to talk about how you're feeling about your illness..."
  • • "Some patients in your situation like to plan ahead..."
  • • "Have you thought about what's most important to you?"
Introducing Palliative Care:

"I'd like to talk about making sure you're as comfortable as possible and that we're focusing on what's most important to you. This is called palliative care, and it works alongside your other treatments."

Discussing Prognosis:
  • • "I wish I could give you more certainty..."
  • • "We're hoping for the best but planning for different possibilities"
  • • "Some people live longer/shorter than we expect"
  • • "I wish I had better news. The scans show that the cancer has spread and is not responding to treatment. This means we're looking at months rather than years."
Exploring Goals & Values:
  • • "What does a good day look like for you?"
  • • "What are you most worried about?"
  • • "If your time becomes limited, what would be most important?"
  • • "Given what we've discussed, what's most important to you now?"

⚠️ Managing Difficult Situations

Anger:
  • • Acknowledge the emotion
  • • Don't take it personally
  • • Explore the underlying fear
  • • Set boundaries if needed
Denial:
  • • Don't force acceptance
  • • Provide information gradually
  • • Check understanding regularly
  • • Respect coping mechanisms

📋 Holistic Assessment Framework

Looking at the whole person and family

🩺 Physical Assessment Priorities

Symptom Assessment:
  • Pain: Location, severity (0-10), character, triggers
  • Breathlessness: At rest/exertion, triggers, anxiety component
  • Nausea/Vomiting: Timing, triggers, bowel function
  • Fatigue: Impact on daily activities
  • Appetite: Weight loss, swallowing difficulties
  • Sleep: Quality, night sweats, anxiety
Focused Examination:
  • Performance Status: ECOG/Karnofsky scale
  • Hydration: Skin turgor, mucous membranes
  • Neurological: Confusion, weakness, reflexes
  • Respiratory: Rate, effort, secretions
  • Cardiovascular: Pulse, BP, peripheral perfusion
  • Abdomen: Distension, masses, bowel sounds
Symptom Assessment Tool Key Questions
Pain 0-10 scale, PAIN assessment Location, character, triggers, relief
Breathlessness MRC dyspnea scale Exertion level, rest symptoms, anxiety
Nausea/Vomiting Frequency, triggers Timing, food relationship, medications
Fatigue 0-10 scale Impact on daily activities, sleep
Appetite Weight loss percentage Food preferences, swallowing

🧠 Psychological Assessment

Screening Questions:
  • • "How are you coping with everything?"
  • • "What worries you most?"
  • • "Are you sleeping okay?"
  • • "Do you feel sad or anxious?"
Red Flags:
  • • Persistent low mood >2 weeks
  • • Panic attacks or severe anxiety
  • • Suicidal thoughts
  • • Complete social withdrawal

👥 Social Assessment

  • Support network: Family, friends, carers
  • Living situation: Home, care home, alone
  • Financial concerns: Benefits, insurance, work
  • Practical needs: Transport, shopping, cleaning
  • Children/dependents: Care arrangements, school support
  • Cultural factors: Language, customs, preferences

🕊️ Spiritual Assessment

Gentle Exploration:
  • • "What gives your life meaning?"
  • • "Do you have any spiritual or religious beliefs?"
  • • "Is there anything you feel you need to do or say?"
  • • "What are you hoping for?"
  • • "What are you worried about?"

Remember: Spiritual care is not about religion - it's about meaning, purpose, and what matters most to the person.

⚠️ Red Flags - Urgent Assessment Needed

  • Spinal cord compression signs
  • Superior vena cava obstruction
  • Hypercalcemia symptoms
  • Massive haemorrhage risk
  • Severe delirium/agitation
  • Uncontrolled pain
  • Respiratory distress
  • Sepsis in context of goals

💊 Symptom Management

Evidence-based approaches to common symptoms

🎯 WHO Analgesic Ladder

Step 1: Mild Pain (1-3/10)

Paracetamol 1g QDS + NSAID (if appropriate)

Step 2: Moderate Pain (4-6/10)

Add weak opioid: Codeine 30-60mg QDS or Tramadol 50-100mg QDS

Step 3: Severe Pain (7-10/10)

Strong opioid: Morphine, Oxycodone, Fentanyl

⚠️ Opioid Prescribing Safety

Key Principles:
  • • Start low, go slow
  • • Regular + breakthrough dosing
  • • Anticipate and prevent side effects
  • • Review and adjust regularly
Side Effect Management:
  • Constipation: Laxatives from day 1
  • Nausea: Antiemetic for first week
  • Drowsiness: Usually settles in 3-5 days
  • Respiratory depression: Rare in cancer pain
Opioid Starting Dose Breakthrough Notes
Morphine IR 5-10mg 4-hourly 1/6 daily dose Gold standard, cheap
Morphine MR 10mg MR twice daily (every 12 hours) Morphine IR Convert when stable
Oxycodone IR 2.5-5mg 4-hourly 1/6 daily dose Less nausea, constipation
Fentanyl patch 12mcg/hr Morphine IR Stable pain only

🫁 Breathlessness Management

Reversible Causes:
  • • Pleural effusion
  • • Pulmonary embolism
  • • Pneumonia/infection
  • • Heart failure
  • • Anemia
  • • Anxiety
Irreversible Causes:
  • • Lung metastases
  • • Lymphangitis carcinomatosa
  • • End-stage COPD
  • • Progressive heart failure
  • • Muscle weakness
Non-pharmacological:
  • • Fan or open window
  • • Positioning (upright, forward lean)
  • • Breathing techniques
  • • Activity pacing
  • • Anxiety management
Pharmacological:
  • Opioids: Morphine 2.5-5mg 4-hourly (strong evidence)
  • Oxygen: If hypoxic (SpO2 <90%) 2-4L/min via nasal cannula
  • Anxiolytics: Lorazepam 0.5mg if anxious
  • • Bronchodilators if appropriate
  • • Steroids for lymphangitis

🤢 Nausea Pathways & Targeted Treatment

Chemoreceptor Trigger Zone (CTZ)

Causes: Drugs, toxins, metabolic

Treatment: Haloperidol 1.5mg ON, Metoclopramide 10mg TDS

Vestibular

Causes: Motion, inner ear, brain mets

Treatment: Cyclizine 50mg TDS, Hyoscine 0.4mg TDS

Gastric Stasis

Causes: Drugs, autonomic dysfunction

Treatment: Metoclopramide 10mg TDS, Domperidone 10mg TDS

Bowel Obstruction

Causes: Mechanical obstruction

Treatment: Cyclizine + Hyoscine butylbromide

Drug Dose Best for Avoid in
Metoclopramide 10mg TDS Gastric stasis, drugs Bowel obstruction, Parkinson's
Cyclizine 50mg TDS Motion, raised ICP Heart failure
Haloperidol 1.5mg ON Opioids, metabolic Parkinson's
Ondansetron 4-8mg TDS Chemotherapy Constipation

📝 Anticipatory Prescribing

Just in case medications for symptom control

💡 Key Principle:

Start Anticipatory Medication if you think the patient has less than 6 months to live. Only costs £30 or so. Allows rapid symptom control without delay. The MINIMUM is an opioid and midazolam.

Symptom Medication Dose Route Frequency Supply
Pain/Breathlessness Morphine Sulfate 2-5mg SC (opioid naive)
Calculate if already on opioids
SC/IM PRN 30min-hourly 10 × 1ml ampoules (10mg/ml)
Agitation/Distress Midazolam 2-5mg SC
(adjust for frailty/background benzos)
SC/Buccal PRN 30min-hourly 10 × 2ml ampoules (10mg in 2ml)
Respiratory Secretions Hyoscine Butylbromide (Buscopan®) 20mg SC SC PRN hourly
Max 120mg/24hrs
10 ampoules (20mg/ml)
Nausea & Vomiting Levomepromazine 2.5-5mg SC SC 12-hourly PRN
(may need hourly initially)
10 ampoules (25mg/ml)

⚠️ Important Safety Points

  • If 3+ doses in 4 hours with little benefit: Seek urgent advice or review
  • If >6 doses in 24 hours: Seek advice or review
  • Always double/triple check calculations - wrong dose can kill
  • Levomepromazine additional use: Terminal agitation/agitated delirium under specialist advice

💉 Syringe Driver Principles

When to Consider Syringe Driver

Indications:

  • • Persistent nausea/vomiting
  • • Dysphagia/unable to swallow
  • • Bowel obstruction
  • • Unconscious/semi-conscious
  • • Poor absorption
  • • Patient preference
Contraindications:
  • • Patient/family refusal
  • • Infection at site
  • • Bleeding disorder
  • • Lack of appropriate support
  • • Drug incompatibilities
🔄 Common Drug Combinations
  • Pain + Nausea: Morphine + Cyclizine (compatible in WFI)
  • Pain + Agitation: Morphine + Midazolam (compatible in WFI)
  • Bowel Obstruction: Cyclizine + Hyoscine butylbromide + Morphine
⚠️ Safety Considerations

Drug Compatibility:

  • • Check compatibility charts
  • • Use water for injection (WFI)
  • • Avoid mixing >3 drugs
  • • Monitor for precipitation

Monitoring:

  • • Site inspection daily
  • • Symptom control assessment
  • • Side effects monitoring
  • • Family education and support

💻 Practical Prescribing Tips

Electronic Systems Support:
  • EMIS/SystmOne: Have sections to make prescribing easier
  • Drop-down boxes: Medication names and doses on Anticipatory Medication charts
  • Syringe Driver charts: Built-in templates available
  • Ardens: Brilliant palliative care section to make life easier

🚨 Palliative Emergencies

Recognizing and managing urgent situations

🚨 The 5 Palliative Care Emergencies

H
Hypercalcaemia
H
severe Haemorrhage
S
neutropenic Sepsis
S
Spinal cord compression
S
Superior vena cava compression

🚨 Spinal Cord Compression - Oncological Emergency

Spinal cord compression is an oncological emergency. Early recognition and treatment can preserve neurological function.

⚠️ Red Flag Symptoms:
  • Pain: Severe back pain, worse at night, band-like
  • Motor: Weakness, heavy legs, difficulty walking
  • Sensory: Numbness, tingling, sensory level
  • Autonomic: Bladder/bowel dysfunction
  • Gait: Unsteady, wide-based gait
🎯 Immediate Actions:
  1. Dexamethasone 16mg PO/IV immediately
  2. Urgent MRI spine (same day)
  3. Oncology referral for radiotherapy
  4. Bed rest until assessment
  5. PPI with steroids
📞 Communication Script:

"I'm calling about [patient name] who I suspect has spinal cord compression. They have [symptoms]. I've given dexamethasone 16mg and they need urgent MRI and oncology review today. This is a potential oncological emergency."

🦴 Hypercalcemia - "Stones, Bones, Groans, Moans"

Symptoms (Stones, Bones, Groans, Moans):
  • Confusion, depression, psychosis
  • Nausea, vomiting, constipation
  • Polyuria, polydipsia, dehydration
  • Bone pain, muscle weakness
  • Fatigue, drowsiness
Severity Guide:
  • Mild: 2.65-2.9 mmol/L
  • Moderate: 3.0-3.4 mmol/L
  • Severe: >3.4 mmol/L
  • Symptoms correlate poorly with level
Severity Treatment Setting Goals of Care
Mild + Asymptomatic Oral fluids, monitor Community Comfort focused
Moderate + Symptomatic IV fluids + bisphosphonate Hospital/hospice Symptom relief
Severe Urgent hospital admission Hospital Discuss with patient/family
Clinical Features:
  • Stones: Kidney stones, polyuria
  • Bones: Bone pain, fractures
  • Groans: Nausea, vomiting, constipation
  • Moans: Confusion, depression, psychosis
Management:
  • IV fluids: 0.9% saline 3-4L/24hrs
  • Bisphosphonate: Zoledronic acid 4mg IV
  • Monitor: U&Es, calcium daily
  • Avoid: Thiazides, calcium, vitamin D

🩸 Massive Haemorrhage

Massive Uncontrollable Haemorrhage can happen in 10-20% of lung cancer patients. It is a horrible thing to have to watch for the patient, their relatives and you. Mortality is super high. So, always write up midazolam for Lung Cancer patients in case this happens.

In the case of massive terminal haemorrhage, give 10mg stat doses IV or IM deltoid/gluteal until the patient is settled.

⚠️ High Risk Situations:
  • • Head/neck cancers near major vessels
  • • Lung cancer with hemoptysis history
  • • GI cancers with previous bleeding
  • • Liver disease with varices
  • • Anticoagulated patients
  • • Thrombocytopenia
📋 Anticipatory Measures:
  • • Dark towels readily available
  • • Midazolam 10mg buccal PRN
  • • Family education about what to expect
  • • Clear plan: call GP/district nurse
  • • Consider stopping anticoagulants
  • • Discuss goals of care
🚨 Acute Management:

If Conscious:

Stay calm, reassure patient, position comfortably

Family Support:

Explain what's happening, stay with them, arrange immediate bereavement support

Decision Making: Hospital transfer rarely appropriate unless clearly reversible cause and good prognosis

💉 Catastrophic haemorrhage PRN medication:
  • • Midazolam 10 mg IM stat if catastrophic bleed / severe distress
  • • May repeat 5–10 mg every 5–10 minutes if required

🫁 Superior Vena Cava Obstruction (SVCO)

Clinical Features:
  • Face/neck: Swelling, plethora, cyanosis
  • Arms: Swelling, prominent veins
  • Chest: Dilated collateral veins
  • Symptoms: Breathlessness, headache, cough
  • Worse: When lying flat, bending forward
Management:
  • Dexamethasone: 16mg daily
  • Position: Sit upright, avoid lying flat
  • Urgent CT chest: Confirm diagnosis
  • Oncology referral: Radiotherapy/stenting
  • Avoid: Central line insertion in arms
⚠️ When to Worry

SVCO can be life-threatening if there is:

  • • Stridor or severe breathlessness
  • • Cerebral edema (confusion, headache)
  • • Rapid onset (hours to days)

🦠 Neutropenic Sepsis

Risk Factors:
  • • Recent chemotherapy
  • • Neutrophil count <0.5
  • • Temperature >38°C
  • • May have minimal signs
Emergency Management:
  • Immediate antibiotics (within 1 hour)
  • Blood cultures before antibiotics
  • IV fluids if hypotensive
  • Urgent hospital admission

🕊️ Care After Death

Verification, certification, and immediate bereavement support

✅ Verification of Death Checklist

Clinical Examination:
  • • No response to verbal/physical stimuli
  • • No heart sounds for 1 minute
  • • No breath sounds for 1 minute
  • • No pupillary response to light
  • • No palpable pulse for 1 minute
Documentation:
  • • Date and time of death
  • • Your name and GMC number
  • • Circumstances of death
  • • Who was present
  • • Any devices removed

📜 Death Certification

When to Refer to Coroner:
  • • Cause of death unknown
  • • Death within 24 hours of admission
  • • Death during/related to surgery
  • • Suspicious circumstances
  • • Industrial disease
  • • Death in custody

💚 Immediate Bereavement Support

Immediate Needs:
  • • Allow time with deceased
  • • Offer tea/coffee and tissues
  • • Explain what happens next
  • • Provide written information
  • • Arrange safe transport home
Practical Support:
  • • Registering the death
  • • Funeral arrangements
  • • Benefits and financial support
  • • Bereavement counseling services
  • • GP follow-up appointment

🤝 Family & Carer Support

Supporting those who care for the dying

👥 Carer Assessment Framework

Physical Impact:
  • • Sleep disruption
  • • Physical exhaustion
  • • Own health problems
  • • Medication management
  • • Manual handling issues
Emotional Impact:
  • • Anticipatory grief
  • • Anxiety and depression
  • • Social isolation
  • • Relationship strain
  • • Guilt and helplessness

🛠️ Practical Support Services

Service Provider How to Access
Respite Care Local Authority/Hospice Social services assessment
District Nursing NHS Community Services GP referral
Equipment/Aids Occupational Therapy Hospital/community OT
Counseling Hospice/Charity Direct referral
Spiritual Care Chaplaincy/Faith Groups Hospital chaplain

💰 Financial Support Options

For Patients:
  • DS1500: Fast-track benefits for terminal illness
  • Personal Independence Payment: Daily living/mobility
  • Employment Support Allowance: If unable to work
  • Universal Credit: Additional elements
For Carers:
  • Carer's Allowance: £76.75/week (2026)
  • Carer's Credit: National Insurance protection
  • Council Tax Reduction: Local authority
  • Flexible Working: Employment rights

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