The universal GP Training website for everyone, not just Bradford.   Created in 2002 by Dr Ramesh Mehay

Sexual Health for GPs: Complete Survival Guide
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Updated Guidelines 2026: New BASHH syphilis guidelines, DoxyPEP recommendations, enhanced LGBTQIA+ care protocols, and comprehensive sexual practices guidance now included.
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Sexual Health for GPs: Your Complete Survival Guide

From awkward conversations to confident care - comprehensive, inclusive, evidence-based

Tea-Friendly Learning For GP Trainees Short on Time Red Flag Focused 🏳️‍🌈 LGBTQIA+ Inclusive 📚 Exam Ready

Date Updated: February 8, 2026

Executive Summary: What You'll Master Today

Because you have 47 other things to do before lunch, and that's just the morning list

What This Page Covers:

  • Consultation Mastery: Setting up safe spaces, taking inclusive histories, and intimate exams
  • Diagnostic Pathways: When to test, treat, or refer for STIs and other conditions
  • Differential Diagnosis: Symptom-led frameworks for common presentations
  • Common Conditions: Confidently managing infections, contraception, and sexual dysfunction
  • Red Flags: Safeguarding, emergencies, and serious pathology you must not miss
  • Exam Relevance: How this is tested in AKT, RCA, and WPBA assessments

Quick Facts at a Glance:

99%
PrEP reduces HIV risk by 99%
Almost 0%
HIV transmission risk from HIV+ person on antivirals with undetectable viral load
1 in 4
Teens will have an STI before age 18
70%
Reduction in genital warts since HPV vaccine introduction
Quick Navigation

Brainy Bites: Essential Sexual Health Wisdom

Key Questions for Data Gathering

Partners, Practices, Protection, Past STIs, Pregnancy intentions. Tailor to time available

Sample phrases:

  • • "Can you tell me about your sexual partners in the last few months?"
  • • "What types of sexual activity do you engage in?"
  • • "How do you protect yourself during sexual activity?"
  • • "Have you ever been diagnosed with a sexually transmitted infection?"
  • • "Are you trying to get pregnant, or trying to avoid pregnancy?"

"How has this affected your relationship/self-esteem?" Context matters as much as the symptom

Sensitive approaches:

  • • "This must be quite worrying for you..."
  • • "How is your partner feeling about this?"
  • • "Has this changed how you feel about intimacy?"
Red Flags – What Not to Miss!

Torsion is a surgical emergency. Assume it's torsion until proven otherwise

  • • Acute onset (<24 hours)
  • • Severe pain, nausea/vomiting
  • • Elevated testis, absent cremasteric reflex
  • • Same-day urology referral essential

PID can cause tubal damage rapidly. Don't delay treatment

  • • Lower abdominal pain + cervical motion tenderness
  • • Fever, abnormal discharge, raised inflammatory markers
  • • Broad-spectrum antibiotics immediately
  • • Urgent referral if systemically unwell

FGM, child sexual exploitation, domestic violence. Know your mandatory reporting duties

  • • FGM in girls <18: Mandatory police reporting within 1 month
  • • Unexplained STIs in children
  • • Signs of coercion or abuse
  • • Document carefully - may be used in court

Common Sexual Diseases for GPs

Sexual Orientation, Sexual Practices, Language and Anatomy
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Based on American Psychological Association guidelines: Language shapes care quality and patient comfort.

✓ Inclusive Language

  • • "Are you in a relationship?" (not "Are you married?")
  • • "Tell me about your partner" (not "boyfriend/girlfriend")
  • • "Do you have sex with men, women, or both?" (not assumptions)
  • • "Sexual orientation" (not "sexual preference")
  • • "Same-gender sexual behavior" (not "homosexual behavior")
  • • "What pronouns do you use?"
  • • "What name would you like me to use?"

✗ Avoid These Terms

  • • "Homosexual" (use "gay" or "lesbian")
  • • "Sexual preference" (implies choice)
  • • "Opposite sex" (use "other gender")
  • • "Normal" relationships (implies others abnormal)
  • • Assuming marital status indicates sexual activity
  • • "Lifestyle choice" (regarding sexual orientation)
  • • "Sexual deviant" or pathologizing language

Key Principles

  • • Use people-first language: "people who are gay" rather than "gays"
  • • Include diverse examples in health education
  • • Don't assume pregnancy risk from all sexual activity
  • • Use parallel terms when comparing groups
  • • Avoid stigmatizing language and stereotypes

LGBTQIA+ Explained

  • L - Lesbian: Woman SEXUALLY ATTRACTED to and WANTING ROMANTIC RELATIONSHIP with another woman
  • G - Gay: Man SEXUALLY ATTRACTED to and WANTING ROMANTIC RELATIONSHIP with another man (or umbrella term)
  • B - Bisexual: SEXUALLY ATTRACTED to and WANTING ROMANTIC RELATIONSHIP with male or female gender
  • T - Transgender: Gender identity differs from birth sex
  • Q - Queer/Questioning: Umbrella term or exploring identity
  • I - Intersex: Born with atypical sex characteristics
  • A - Asexual: Little to no sexual attraction
  • + - Plus: Includes all other identities
Common Orientations
  • Heterosexual/Straight: SEXUALLY ATTRACTED to and WANTING ROMANTIC RELATIONSHIP with the opposite gender
  • Gay/Lesbian: SEXUALLY ATTRACTED to and WANTING ROMANTIC RELATIONSHIP with the same gender
  • Bisexual: SEXUALLY ATTRACTED to and WANTING ROMANTIC RELATIONSHIP with either male or female gender
  • Pansexual: SEXUALLY ATTRACTED to and WANTING ROMANTIC RELATIONSHIP with anyone, regardless of gender
  • Asexual: Little to no sexual attraction
Behavioral vs Identity
  • MSM: Men who have Sex with Men (behavior, not identity) - usually want relationship with females, and sexually attracted to females, but also like sexual acts with men, even though they usually dont find men particularly attractive nor do they want a relationship with them.
  • Heteroflexible: Mostly heterosexual (sexually attracted to & want relationship with opposite sex) but sometimes have other-gender attraction.
  • Homoflexible: Mostly homosexual (sexually attracted to and want relationship with same sex), but sometimes have different-gender attraction
  • Note: Behavior ≠ Identity. Some MSM don't identify as gay/bisexual
Gender Identity
  • Cisgender: Gender identity matches birth sex
  • Transgender: The person feels deeply inside that they are different from the gender they were born with. Imagine what you are now and tommorrow, you wake up inside the body of the opposite sex? How would you feel? This is exactly how trans people feel, although they did not wake up overnight with it.
  • Non-binary: A person does not relate to feeling male nor female
  • Gender fluid: Somedays a person feels male, other days more female, and possibly other days, something else.
  • Agender: Someone does not particularly feel male or female or anything else.
Important Distinctions
  • Transgender vs Transvestite: The first is to do with identity, the transgender person feels deeply inside of a gender different to what they were born with. A transvestite is a person who is comfortable with the gender they were born with, but prefers to wear clothing of the opposite gender usually for sexual gratification or expression.
  • Binary vs Non-binary: Binary - means a person relates to being male or female. Non-binary - a person does not relate to feeling male nor female.
  • Pronouns: Most cis-males and trans-males prefer to be called he/him. Most cis-females and trans-females prefer to be called she/her. Most non-binary prefer to be called they/them. The latter might sound odd to you, but it is only because you are not used to saying it. Grammatically it is correct and not wierd. If you feel it feels weird to you, it means you have some learning and development needs.
  • Intersex: Born with atypical sex characteristics (formerly "hermaphrodite" - outdated term)
  • Note: Always use person's chosen name and pronouns
ℹ️
Understanding diverse sexual practices helps provide appropriate risk assessment and harm reduction advice.
PracticeDescriptionSTI RisksHarm Reduction
Oral SexMouth-to-genital contactHSV, HPV, gonorrhoea, syphilis, chlamydiaCondoms, dental dams, avoid if oral lesions
Anal SexPenetration of anusHighest HIV risk, all STIs, hepatitisCondoms, PrEP if high risk, adequate lubrication
Vaginal SexPenetration of vaginaAll STIs, pregnancy riskCondoms, contraception, regular testing
RimmingOral-anal contactHepatitis A/B, parasites, bacterial infectionsDental dams, hepatitis vaccination, hygiene
FistingHand/fist insertion into vagina or anusTrauma, blood-borne viruses, bacterial infectionsGloves, adequate lubrication, gradual progression
Sex ToysUse of objects for sexual pleasureCross-contamination, trauma if inappropriate objectsClean between partners, condoms on toys, body-safe materials
ChemsexSex under influence of drugsIncreased risk-taking, sharing equipmentHarm reduction services, addiction support, regular testing
Poppers UseAlkyl nitrites inhaled for anal muscle relaxation but others use it for a little "high" sexual feeling.Increased risk-taking, potential for traumaAvoid with erectile dysfunction medications, use in ventilated areas
Group SexMultiple partners simultaneouslyMultiple exposures, cross-contaminationFresh condoms between partners, regular testing
Polyamory/ThrouplesMultiple romantic relationships (this is becoming more common)Network transmission risksCommunication, testing agreements, barrier methods

Clinical Approach

  • • Ask about specific practices, not just "sexually active"
  • • Tailor STI screening to practices engaged in
  • • Provide non-judgmental harm reduction advice
  • • Consider extra-genital testing (throat, rectum) for MSM
  • • Discuss PrEP for high-risk individuals

Penis Size: Facts for Patient Reassurance

Average Measurements
  • • Flaccid length: 9.16 cm (3.6 inches)
  • • Erect length: 13.12 cm (5.17 inches)
  • • Erect circumference: 11.66 cm (4.59 inches)
  • • Normal range: 10-18 cm when erect
Key Messages
  • • Size does NOT determine sexual satisfaction
  • • Technique and communication matter more
  • • Most vaginal nerve endings in outer third
  • • Reassure patients about normal variation
Data-Gathering & Examination Tips
Under-16s: Fraser Guidelines

Apply Fraser guidelines (Gillick competence). Confidentiality can be maintained if the young person:

  • • Understands the advice and its implications
  • • Cannot be persuaded to involve parents
  • • Is likely to have sex without treatment/advice
  • • Their physical/mental health would suffer without advice
Essential Elements
  • Chaperones: Always offer for intimate examinations. Document offer and response
  • Inclusive Language: Ask about preferred name and pronouns
  • Documentation: Clear, factual notes. Include relevant negatives
  • Safety-netting: Clear advice on when to return
What to Say
  • • "Everything we discuss is confidential..."
  • • "I'd like to offer you a chaperone for the examination"
  • • "What name would you like me to use?"
  • • "What pronouns do you use?"
STI Risk Assessment (The 5 P's)
  • Partners: Number, gender, concurrency
  • Practices: Vaginal, anal, oral
  • Protection: Condom use consistency
  • Past History: Previous STIs, tests
  • Pregnancy Intention: Contraception needs
Sample Questions:
  • • "How many sexual partners have you had in the last 3 months?"
  • • "What types of sexual activity do you engage in?"
  • • "How often do you use condoms?"
  • • "Have you ever had an STI?"
Contraception Consultation Structure
  • • Medical eligibility (UKMEC criteria)
  • • Efficacy, advantages, disadvantages
  • • Patient preferences and lifestyle fit
  • • Follow-up and troubleshooting plans
Key Questions:
  • • "What's most important to you in contraception?"
  • • "How do you feel about daily methods?"
  • • "Any concerns about procedures?"
Unwanted Pregnancy Approach
  • • Explore sensitively: preferences, safety, immediate risks
  • • Safeguarding assessment (coercion, abuse)
  • • Non-directive counselling on all options
  • • Clear signposting to appropriate services
Always obtain explicit consent and offer a chaperone for intimate examinations.
Female Genital Examination
Indications:
  • • Abnormal bleeding, discharge, pain
  • • Suspected PID, foreign body
  • • Contraceptive device issues
Approach:
  • • Explain each step clearly
  • • Visual inspection first
  • • Speculum if needed
  • • Look for: discharge, lesions, ulcers, warts, atrophy, FGM
Vaginal pH Testing & Swabs
  • • pH >4.5 suggests bacterial vaginosis or trichomoniasis
  • • Self-taken vulvovaginal swabs acceptable for chlamydia/gonorrhoea
  • • Clinician-taken swabs needed for microscopy

Common pitfall:

Using lubricant on swabs can affect test results

Key Phrases for Sensitive Sexual Health Enquiries

"I'd like to ask you some questions about your sexual health. This is a routine part of healthcare, and everything we discuss is confidential."

"These questions might seem personal, but they help me provide you with the best care possible."

"I ask all my patients these questions - it's nothing to be embarrassed about."

"Are you currently in a sexual relationship?"

"Can you tell me about your sexual partners in the last few months?"

"Do you have sex with men, women, or both?"

"How would you describe your sexual orientation?"

"What types of sexual activity do you engage in?"

"This includes vaginal, oral, or anal sex - I need to know to provide appropriate testing."

"Do you use any sex toys or engage in other sexual practices?"

Diagnostic Approach & Investigations

Investigate vs. Treat vs. Refer - Navigating the "what next" after a sexual health presentation

Opportunistic Screening (NICE NG221 recommends):
  • • All sexually active under-25s annually (chlamydia)
  • • New sexual partners or change in partner
  • • Men who have sex with men (MSM) - 3-monthly if high risk
  • • Pre-conception or antenatal booking
  • • HIV testing in high prevalence areas (>2/1000) offered to all new registrants
Symptomatic Testing Indications:
  • • Abnormal vaginal/urethral discharge
  • • Dysuria, frequency, urgency
  • • Genital ulcers, lumps, or lesions
  • • Pelvic pain or abnormal bleeding
  • • Partner notification from STI diagnosis
Testing Frequency for High-Risk Groups:
Gay Men & MSM:
  • • HIV, syphilis: Every 3 months
  • • Chlamydia, gonorrhoea: Every 3 months
  • • Hepatitis B: Annually (if not immune)
  • • Include throat and rectal swabs
Women at Higher Risk:
  • • Multiple partners: Every 6 months
  • • Sex workers: Every 3 months
  • • Partner of MSM: Every 6 months
  • • Cervical screening as per guidelines
PresentationFirst-line TestsAdditional TestsWhen to Refer
Abnormal dischargepH, microscopy, chlamydia/gonorrhoea NAATTrichomonas PCR if high riskRecurrent symptoms, treatment failure
Fishy odourpH, microscopy (clue cells)Whiff test (KOH)Recurrent BV (>3 episodes/year)
Cottage cheese dischargepH, microscopy (spores/hyphae)Candida culture if recurrentRecurrent thrush (>4 episodes/year)
Frothy yellow dischargeTrichomonas PCR, chlamydia/gonorrhoeaFull STI screenAlways refer for contact tracing
Available Self-Testing Options:
HIV Self-Testing:
  • • Oral fluid or fingerprick tests
  • • Results in 15-20 minutes
  • • Window period: 12 weeks
  • • Reactive results need confirmation
STI Postal Testing:
  • • Chlamydia/gonorrhoea: Urine or swab
  • • Syphilis/HIV: Fingerprick blood
  • • Available through SH:24, local services
  • • Results via text/online portal
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Patient Counselling: Explain window periods, limitations, and importance of professional follow-up for positive results.
Same-Day Referrals:
  • • Suspected testicular torsion
  • • Severe PID with systemic symptoms
  • • Suspected sexual assault (within 72 hours for forensics)
  • • Paraphimosis or severe balanitis
  • • Suspected ectopic pregnancy
Urgent (within 48 hours):
  • • Suspected gonorrhoea (high resistance rates)
  • • Primary syphilis (infectious)
  • • Suspected herpes in pregnancy
  • • Complicated STI in immunocompromised
  • • Safeguarding concerns
Differential Diagnosis Frameworks

Symptom-Led Differentials - Pattern recognition for common sexual health presentations

ConditionDischarge CharacteristicsAssociated SymptomsKey Diagnostic Features
Bacterial VaginosisThin, grey, fishy odourUsually asymptomatic, mild itchpH >4.5, clue cells, positive whiff test
CandidaThick, white, cottage cheeseIntense itch, dysuria, dyspareuniapH <4.5, spores/hyphae on microscopy
TrichomoniasisFrothy, yellow-green, offensiveDysuria, frequency, strawberry cervixpH >4.5, motile organisms on microscopy
ChlamydiaMucopurulent or absentOften asymptomatic, dysuria, bleedingNAAT positive, cervical friability
GonorrhoeaPurulent, yellow-greenDysuria, pelvic pain, feverNAAT positive, gram-negative diplococci
PhysiologicalClear/white, cyclical variationNo itch, odour, or painpH 3.8-4.5, normal lactobacilli
Clinical Pearls:
  • • Mixed infections are common - test for multiple causes
  • • Absence of symptoms doesn't rule out STIs
  • • Consider atrophic vaginitis in post-menopausal women
  • • Foreign body (retained tampon) can mimic infection
ConditionUlcer CharacteristicsPainAssociated FeaturesDiagnosis
HSV (Primary)Multiple, shallow, vesicles → ulcersVery painfulFever, malaise, lymphadenopathyPCR swab, serology
HSV (Recurrent)Fewer, smaller ulcersMild-moderate painProdromal tingling, shorter durationClinical, PCR if atypical
Primary SyphilisSingle, indurated, clean basePainlessRegional lymphadenopathyDark field microscopy, serology
Behçet's DiseaseDeep, well-demarcatedVery painfulOral ulcers, eye symptoms, arthritisClinical criteria, exclude infections
Aphthous UlcersShallow, yellow base, red haloPainfulRecurrent, stress-relatedClinical, exclude other causes
TraumaVariable, history of injuryVariableClear precipitantHistory, exclude infection
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Red Flag: Any persistent, non-healing genital ulcer should be biopsied to exclude malignancy.
Superficial Dyspareunia (Entry Pain)
  • Infections: Candida, HSV, bacterial vaginosis
  • Dermatological: Lichen sclerosus, eczema, contact dermatitis
  • Anatomical: Tight hymen, vaginal stenosis
  • Hormonal: Atrophic vaginitis (menopause, breastfeeding)
  • Psychological: Vaginismus, anxiety, trauma history
Deep Dyspareunia (Deep Pelvic Pain)
  • Gynaecological: Endometriosis, ovarian cysts, fibroids
  • Inflammatory: PID, chronic pelvic pain syndrome
  • Anatomical: Retroverted uterus, pelvic adhesions
  • Bowel: IBS, constipation, inflammatory bowel disease
  • Urological: Interstitial cystitis, urethral syndrome
Assessment Approach:
  • • Detailed sexual history including timing, triggers, positions
  • • Relationship factors, psychological wellbeing, trauma history
  • • Examination: external genitalia, single-finger examination first
  • • Consider Q-tip test for vulvodynia/vestibulodynia
  • • Pelvic examination if tolerated - assess for masses, tenderness
Bleeding PatternCommon CausesKey FeaturesInitial Management
Post-coital bleedingCervical ectropion, polyps, cancer, infectionsBleeding after intercourseSpeculum exam, cervical screening, STI testing
Intermenstrual bleedingHormonal contraception, polyps, fibroids, cancerBleeding between periodsPregnancy test, pelvic exam, consider imaging
Heavy menstrual bleedingFibroids, adenomyosis, endometrial pathology>80ml/cycle or subjective heavinessFBC, TFTs, consider transvaginal USS
Post-menopausal bleedingAtrophy, HRT, endometrial cancer, polypsAny bleeding >12 months post-menopauseUrgent 2-week wait referral
Breakthrough bleedingMissed pills, drug interactions, infectionsBleeding on hormonal contraceptionReview compliance, STI screen, consider change
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Red Flags: Post-menopausal bleeding = cancer until proven otherwise. Urgent referral required.
Treatment & Prevention

STI Treatments, Contraception & Prevention Strategies

Updated 2026: Treatment recommendations based on latest BASHH guidelines. Always check local antimicrobial resistance patterns.
ConditionFirst Line TreatmentAlternativeNotes
Chlamydia (uncomplicated)Doxycycline 100mg BD × 7 daysAzithromycin 1g day 1, then 500mg × 2 daysTest of cure not routinely needed. Partner notification essential
GonorrhoeaRefer to GUMIf urgent: Ceftriaxone 1g IM + Azithromycin 1g POHigh resistance rates - culture essential. Always dual therapy
Syphilis (early)Refer to GUMBenzathine penicillin 2.4MU IM (single dose)Partner notification essential. Follow-up serology needed
HSV (first episode)Aciclovir 400mg TDS × 5 daysValaciclovir 500mg BD × 5 daysStart within 72 hours. Extend to 10 days if severe
HSV (recurrent)Aciclovir 800mg TDS × 2 daysSuppressive therapy if ≥6 episodes/yearPatient-initiated therapy. Start within 24 hours
Bacterial VaginosisMetronidazole 400mg BD × 5-7 daysMetronidazole gel 0.75% × 5 daysAvoid alcohol during treatment. Partner treatment not needed
Candida (uncomplicated)Fluconazole 150mg single doseClotrimazole pessary 500mg single doseTopical treatments safe in pregnancy
TrichomoniasisMetronidazole 2g single doseMetronidazole 400mg BD × 7 daysAlways treat partner. Test of cure at 4 weeks
Important Treatment Principles:
  • • Always treat sexual partners for STIs (except BV and candida)
  • • Advise abstinence until treatment completed and symptoms resolved
  • • Follow up positive results and ensure treatment completion
  • • Consider expedited partner therapy where appropriate
  • • Document partner notification attempts
InfectionDischarge AppearanceOdourpHItch/PainOther Features
Bacterial VaginosisThin, grey, homogeneousFishy, especially after sex>4.5Minimal itchClue cells, positive whiff test
CandidaThick, white, cottage cheeseYeasty/bread-like<4.5Intense itch, burningVulval erythema, satellite lesions
TrichomoniasisFrothy, yellow-greenOffensive, musty>4.5Itch, dysuriaStrawberry cervix, motile organisms
ChlamydiaMucopurulent or noneNone or mildVariableOften asymptomaticCervical friability, bleeding
GonorrhoeaPurulent, yellowNone to offensiveVariableDysuria, pelvic painCervical inflammation, systemic symptoms
NormalClear to white, cyclicalNone or mild3.8-4.5NoneLactobacilli predominant
Atrophic VaginitisScant, may be bloodyNone>4.5Dryness, dyspareuniaPale, thin vaginal walls
Clinical Pearls for Recognition:
  • Fishy odour + grey discharge = BV (most reliable combination)
  • Cottage cheese + intense itch = Candida (classic presentation)
  • Frothy + offensive = Trichomoniasis (always STI screen)
  • No symptoms ≠ no infection (chlamydia often asymptomatic)
  • Mixed infections common (test for multiple causes)
  • pH testing is quick and helpful (normal <4.5)
LARC (Long-Acting Reversible Contraception) - First Choice
MethodEfficacyDurationKey BenefitsMain Considerations
Mirena IUS>99%5 yearsReduces menstrual bleedingInitial irregular bleeding
Copper IUD>99%10 yearsHormone-free, immediate fertility returnMay increase bleeding/pain
Implant>99%3 yearsConvenient, reversibleUnpredictable bleeding patterns
Depo injection>99%12 weeksPrivate, reduces periodsDelayed fertility return, bone density
Emergency Contraception
Levonorgestrel (Levonelle):
  • • 1.5mg single dose
  • • Up to 72 hours post-UPSI
  • • Less effective after 24 hours
  • • Available over-the-counter
Ulipristal (ellaOne):
  • • 30mg single dose
  • • Up to 120 hours post-UPSI
  • • More effective than levonorgestrel
  • • Prescription only

Copper IUD: Most effective emergency contraception up to 5 days post-UPSI or ovulation

Barrier Methods & Safer Sex
Male Condoms:
  • • 98% effective when used correctly
  • • Protect against most STIs
  • • Use with water-based lubricant
  • • Check expiry dates and storage
Female Condoms & Dental Dams:
  • • Female condoms: 95% effective
  • • Dental dams for oral-genital/anal contact
  • • Can be inserted up to 8 hours before
  • • User-controlled protection
Vaccination Programs
HPV Vaccination:
  • • Routine at age 12-13 (both sexes)
  • • Catch-up to age 25 for MSM
  • • Protects against cancer-causing types
  • • 70% reduction in genital warts
Hepatitis B:
  • • Routine in infancy
  • • Offer to high-risk adults
  • • MSM, sex workers, multiple partners
  • • Check immunity before vaccination
Harm Reduction Counselling
  • Risk reduction: Fewer partners, mutual monogamy, regular testing
  • Substance use: Avoid chemsex, don't share equipment
  • Communication: Discuss STI status with partners
  • Regular screening: Tailor frequency to risk level
  • Treatment as prevention: Undetectable = untransmittable (U=U)
Red Flags & Conditions Not to Miss

Safeguarding and Emergencies

Mandatory Reporting Requirements
  • FGM in girls <18: Report to police within 1 month (mandatory)
  • Child sexual abuse: Any STI in prepubertal child
  • Sexual assault: Recent assault requiring forensic examination
  • Trafficking: Multiple STIs, signs of control/coercion
Warning Signs to Recognize
Domestic Violence:
  • • Controlling partner behavior
  • • Unexplained injuries
  • • Fear of partner's reaction
  • • Isolation from support networks
Sexual Exploitation:
  • • Multiple STIs in young person
  • • Older partner with significant age gap
  • • Gifts, money, accommodation provided
  • • Substance use, missing from home/school
Documentation & Action
  • • Document concerns clearly and factually
  • • Use patient's own words in quotes
  • • Body maps for injuries (if consent given)
  • • Know local safeguarding procedures
  • • Involve safeguarding lead/social services
  • • Consider safety planning with patient
PresentationKey FeaturesImmediate ActionTimeframe
Testicular TorsionSudden severe testicular pain, nausea, high-riding testisUrgent urology referralSame day (<6 hours optimal)
Severe PIDPelvic pain + fever + systemic symptomsIV antibiotics, urgent gynae referralSame day
ParaphimosisRetracted foreskin causing constrictionAttempt reduction, urgent urology if failsSame day
Fournier's GangreneNecrotizing fasciitis of genitalsIV antibiotics, emergency surgeryImmediate (life-threatening)
Ectopic PregnancyPelvic pain + bleeding + positive pregnancy testUrgent gynae assessmentSame day
Sexual AssaultRecent assault (<72 hours)SARC referral, forensic examinationImmediate (evidence preservation)
🚨
Remember: When in doubt, refer urgently. Better safe than sorry with potential emergencies.
2-Week Wait Referral Criteria
Gynecological Cancers:
  • • Post-menopausal bleeding
  • • Unexplained vulval lump/ulceration
  • • Persistent pelvic mass
  • • Cervical mass on examination
Urological Cancers:
  • • Testicular lump (any age)
  • • Penile lesion/ulceration
  • • Persistent scrotal swelling
  • • Unexplained hematuria
HPV-Related Cancers
  • Cervical: Regular screening, investigate abnormal bleeding
  • Anal: Consider in high-risk MSM, HIV+ patients
  • Oropharyngeal: Increasing incidence, especially in men
  • Vulval/Vaginal: Persistent lesions, especially in older women
  • Penile: Any persistent lesion, especially if ulcerated
Clinical Examination Red Flags
  • Hard, fixed lumps: Suggest malignancy
  • Non-healing ulcers: Biopsy required
  • Irregular bleeding patterns: Investigate thoroughly
  • Unexplained weight loss: Consider systemic disease
  • Lymphadenopathy: May indicate metastatic spread
How This Topic Is Tested - Exam-Focused Preparation
High-Yield Topics for AKT
Clinical Knowledge:
  • • STI treatment regimens (especially chlamydia)
  • • Contraception efficacy rates and UKMEC criteria
  • • Emergency contraception timeframes
  • • Cervical screening guidelines
  • • Fraser guidelines for under-16s
Guidelines & Evidence:
  • • NICE guidelines on STI reduction
  • • BASHH treatment recommendations
  • • FSRH contraception guidance
  • • Safeguarding procedures
  • • Partner notification requirements
Sample AKT-Style Questions

Q: A 19-year-old woman has a positive chlamydia test. What is the first-line treatment?

A: Doxycycline 100mg BD for 7 days

Q: A 15-year-old requests contraception. Under Fraser guidelines, you can provide this without parental consent if:

A: She understands the advice and cannot be persuaded to involve parents

Communication Skills Assessment
Data Gathering:
  • • Use inclusive, non-judgmental language
  • • Explore ICE (Ideas, Concerns, Expectations)
  • • Take comprehensive sexual history (5 P's)
  • • Address confidentiality early
Clinical Management:
  • • Explain examination process clearly
  • • Discuss treatment options and side effects
  • • Address partner notification sensitively
  • • Provide clear safety-netting advice
Common RCA Scenarios
  • • Young person requesting contraception
  • • Patient with STI symptoms needing testing
  • • Contraception counseling and method selection
  • • Breaking bad news (positive STI result)
  • • Emergency contraception consultation
  • • Sexual dysfunction or relationship problems
Case-Based Discussion (CBD) Topics
  • • Complex contraception cases (multiple comorbidities)
  • • STI contact tracing and partner notification
  • • Safeguarding concerns in sexual health
  • • Managing treatment failures or complications
  • • Ethical dilemmas (confidentiality vs. public health)
Clinical Observation Tool (COT) Skills
Consultation Skills:
  • • Establishing rapport and trust
  • • Sensitive history taking
  • • Appropriate examination technique
  • • Clear explanation of findings
Professional Skills:
  • • Maintaining confidentiality
  • • Recognizing limitations
  • • Appropriate referral decisions
  • • Documentation standards
Recommended Learning Opportunities
Clinical Attachments:
  • • GUM clinic sessions
  • • Family planning clinics
  • • Young people's sexual health services
  • • Gynecology outpatients
Skills Development:
  • • IUD/IUS insertion training
  • • Contraceptive implant procedures
  • • Cervical screening updates
  • • Safeguarding training
Portfolio Evidence
  • Significant Event Analysis: STI outbreak, safeguarding case
  • Audit: Contraception prescribing, STI testing rates
  • Quality Improvement: Improving sexual health services
  • Learning Log: Reflect on challenging cases
  • Patient Feedback: Sexual health consultation experiences

HIV: What GPs Need to Know

HIV Disease Stages & Symptoms
Early HIV (Seroconversion Illness) - 2-6 weeks post-infection
Common Symptoms (50-90%):
  • • Fever, malaise, fatigue
  • • Maculopapular rash (trunk, face)
  • • Lymphadenopathy
  • • Sore throat, mouth ulcers
  • • Headache, myalgia
Less Common:
  • • Diarrhea, nausea, vomiting
  • • Genital ulceration
  • • Neurological symptoms
  • • Thrombocytopenia

Key: Often mistaken for flu/glandular fever. High viral load = highly infectious

Chronic HIV (Asymptomatic Phase) - Years to decades
  • • Usually asymptomatic
  • • Gradual CD4+ T-cell decline
  • • May have persistent generalized lymphadenopathy
  • • Increased susceptibility to infections
  • • Without treatment: CD4 count falls ~50-100 cells/year
Advanced HIV/AIDS (CD4 <200 cells/μL)
Opportunistic Infections:
  • • Pneumocystis pneumonia (PCP)
  • • Candida esophagitis
  • • CMV retinitis
  • • Toxoplasmosis
  • • Mycobacterium avium complex
AIDS-defining Cancers:
  • • Kaposi's sarcoma
  • • Non-Hodgkin lymphoma
  • • Cervical cancer
  • • Primary CNS lymphoma
ℹ️
GP Role: Early recognition of seroconversion illness, appropriate testing, and prompt referral to HIV services.
HIV Treatment: GP Knowledge Level
Modern HIV Treatment Principles
  • Start immediately: Treatment recommended for all HIV+ patients regardless of CD4 count
  • Combination therapy: Usually 3 drugs from 2+ classes (HAART)
  • Goal: Undetectable viral load (<50 copies/mL)
  • U=U: Undetectable = Untransmittable (no sexual transmission risk)
  • Adherence crucial: >95% adherence needed to prevent resistance
Drug ClassCommon ExamplesMechanismKey Side EffectsGP Monitoring
NRTIs
(Nucleoside RTIs)
Zidovudine (AZT)
Tenofovir
Emtricitabine
Block reverse transcriptaseLactic acidosis, lipodystrophy, renal toxicityFBC, U&Es, LFTs
NNRTIs
(Non-nucleoside RTIs)
Efavirenz
Rilpivirine
Block reverse transcriptaseRash, CNS effects, hepatotoxicityLFTs, psychiatric symptoms
Protease InhibitorsRitonavir
Darunavir
Atazanavir
Block viral proteaseGI upset, lipid abnormalities, diabetesLipids, glucose, drug interactions
Integrase InhibitorsDolutegravir
Raltegravir
Bictegravir
Block integration into host DNAGenerally well tolerated, weight gainWeight, mood changes
GP Role in HIV Care
Shared Care Responsibilities:
  • • Routine health maintenance
  • • Cardiovascular risk assessment
  • • Cancer screening (enhanced)
  • • Mental health support
  • • Drug interaction checking
When to Involve Specialist:
  • • Treatment failure or resistance
  • • Significant side effects
  • • Opportunistic infections
  • • Pregnancy planning
  • • Complex drug interactions
⚠️
Drug Interactions: HIV medications have numerous interactions. Always check before prescribing new medications.
PrEP, PEP & DoxyPEP: Complete Guide
2026 Update: DoxyPEP now recommended by BASHH for high-risk individuals. PrEP access expanded across the UK.
PrEP Regimens & Efficacy
RegimenDosingEfficacyBest For
Daily PrEPTenofovir/Emtricitabine daily99% reduction in HIV riskRegular sexual activity, all genders
Event-based PrEP2-1-1 dosing around sex86% reduction (MSM only)Infrequent sexual activity, MSM
PrEP Eligibility Criteria
  • • MSM with condomless anal sex in last 6 months
  • • Heterosexual men/women from high-prevalence areas
  • • People who inject drugs sharing equipment
  • • Sexual partners of HIV+ individuals not on treatment
  • • Sex workers at ongoing risk
  • • Transgender individuals at high risk
PrEP Monitoring Requirements
Before Starting:
  • • HIV test (4th generation)
  • • Hepatitis B surface antigen
  • • eGFR and urinalysis
  • • Full STI screen
Ongoing (3-monthly):
  • • HIV testing
  • • STI screening
  • • Renal function
  • • Adherence support
PEP Urgency & Timing
  • Start within 72 hours of exposure (ideally <24 hours)
  • 28-day course of combination antiretrovirals
  • Risk assessment essential - not indicated for all exposures
  • Follow-up testing at 6 weeks, 3 months, 6 months
Exposure TypeRisk LevelPEP RecommendationAdditional Considerations
Receptive anal intercourseHighRecommendedHighest transmission risk
Insertive anal intercourseModerateConsiderAssess source viral load
Receptive vaginal intercourseModerateConsiderHigher risk if menstruating
Insertive vaginal intercourseLow-moderateConsiderRisk varies with viral load
Oral sexVery lowNot usually recommendedConsider if oral ulceration
Needlestick injuryLowConsiderAssess needle type and source
PEP Regimen (Standard)
  • Tenofovir/Emtricitabine (Truvada) 1 tablet daily
  • Plus Raltegravir 400mg twice daily
  • Duration: 28 days exactly
  • Side effects: Nausea, diarrhea, headache, fatigue
  • Adherence crucial: Missing doses reduces efficacy
🆕
New 2026: DoxyPEP now recommended by BASHH for preventing bacterial STIs in high-risk individuals.
DoxyPEP Protocol
  • Dose: Doxycycline 200mg single dose
  • Timing: Within 24-72 hours after condomless sex
  • Maximum: Once daily (don't repeat if multiple exposures same day)
  • Efficacy: ~65% reduction in chlamydia, gonorrhoea, syphilis
DoxyPEP Eligibility
Recommended For:
  • • MSM with recent bacterial STI
  • • MSM on PrEP with high STI risk
  • • Transgender women with high STI risk
  • • Consider for other high-risk groups
Contraindications:
  • • Doxycycline allergy
  • • Pregnancy/breastfeeding
  • • Children under 12 years
  • • Concurrent tetracycline use
DoxyPEP Considerations
  • Resistance concerns: Monitor local resistance patterns
  • Not effective against: Herpes, HIV, hepatitis
  • Side effects: GI upset, photosensitivity, esophagitis
  • Regular STI screening still essential
  • Counseling: Not a substitute for safer sex practices
You've Got This! 💪

Remember: You don't need to be a sexual health specialist to provide excellent sexual healthcare. You just need to know when to worry (red flags), when to treat (primary care management), and when to refer (specialist services).

Key Takeaways:

  • • Create a safe, non-judgemental space using inclusive language
  • • Use structured approaches for history-taking (5 P's framework)
  • • Know your safeguarding duties and mandatory reporting requirements
  • • Understand the common conditions you can manage and when to escalate
  • • Sexual health conversations get easier with practice - your inclusive approach makes a difference
Now go reward yourself with that well-deserved coffee ☕

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